Uses of Abilify Back to Top. Oral and Immediate-Release Injectable: Abilify is a prescription medication used to treat: schizophrenia in people age 13 years and older bipolar I disorder in people age 10 years and older, including: manic or mixed episodes that happen with bipolar I disorder manic or mixed episodes that happen with bipolar I disorder, when used with the medicine lithium or valproate long-term treatment of bipolar I disorder major depression in adults, as an add-on treatment to an antidepressant medicine when you do not get better with an antidepressant alone irritability associated with autistic disorder in children and adolescents ages 6 to 17 years old agitation associated with schizophrenia or bipolar disorder This medication may be prescribed for other uses.
Manufacturer Back to Top. Otsuka America Pharmaceutical, Inc. Generic Back to Top. Aripiprazole For more information on this medication choose from the list of selections below.
Abilify Drug Class Back to Top. Abilify is part of the drug class: Other antipsychotics. Side Effects of Abilify Back to Top. Serious side effects have been reported with Abilify.
See "Abilify Precautions" section. Abilify Interactions Back to Top. Especially tell your doctor if you take: antidepressants mood elevators antifungals such as itraconazole Sporanox and ketoconazole Nizoral antihistamines bupropion Wellbutrin carbamazepine Tegretol clarithromycin Biaxin fluoxetine Prozac, Sarafem HIV protease inhibitors such as atazanavir Reyataz , indinavir Crixivan , nelfinavir Viracept , ritonavir Norvir , and saquinavir Invirase ipratropium Atrovent medications for anxiety, high blood pressure, irritable bowel syndrome, mental illness, motion sickness, Parkinson's disease, seizures, ulcers, or urinary problems nefazodone Serzone paroxetine Paxil, Pexeva quinidine Cardioquine, Quinact, Duraquin rifampin Rifadin, Rimactane sedatives sleeping pills telithromycin Ketek tranquilizers This is not a complete list of Abilify drug interactions.
Abilify Precautions Back to Top. Tell your healthcare provider right away if you have some or all of the following symptoms of this life-threatening nervous system disorder: high fever stiff muscles confusion sweating changes in pulse, heart rate, and blood pressure high blood sugar. Increases in blood sugar can happen in some people who take Abilify. Call your healthcare provider if you have any of these symptoms of high blood sugar while taking Abilify: feel very thirsty need to urinate more than usual feel very hungry feel weak or tired feel sick to your stomach feel confused, or your breath smells fruity Increase in weight.
Weight gain has been reported in patients taking medicines like Abilify, so you and your healthcare provider should check your weight regularly. For children and adolescent patients 6 to 17 years of age weight gain should be compared against that expected with normal growth. This may lead to aspiration and choking. Call your healthcare provider about any movements you cannot control in your face, tongue, or other body parts.
These may be signs of a serious condition. Tardive dyskinesia may not go away, even if you stop taking Abilify. Tardive dyskinesia may also start after you stop taking Abilify.
Lightheadedness or fainting can occur when rising too quickly from a sitting or lying position. Low white blood cell count Seizures convulsions Problems controlling your body temperature so that you feel too warm. Avoid getting over-heated or dehydrated. Do not over-exercise. In hot weather, stay inside in a cool place if possible. Stay out of the sun. Do not wear too much or heavy clothing.
Drink plenty of water while taking Abilify. Important information about antidepressant medicines: Never stop an antidepressant medicine without first talking to a healthcare provider. Stopping an antidepressant medicine suddenly can cause other symptoms.
Antidepressants are medicines used to treat depression and other illnesses. It is important to discuss all the risks of treating depression and also the risks of not treating it. Patients and their families or other caregivers should discuss all treatment choices with the healthcare provider, not just the use of antidepressants.
Antidepressant medicines have other side effects. Talk to the healthcare provider about the side effects of the medicine prescribed for you or your family member. Antidepressant medicines can interact with other medicines. Know all of the medicines that you or your family member takes. Keep a list of all medicines to show the healthcare provider. Do not start new medicines without first checking with your healthcare provider.
Not all antidepressant medicines prescribed for children are FDA approved for use in children. Abilify Food Interactions Back to Top. Inform MD Back to Top. Before you receive Abilify, tell your healthcare provider if you: have never taken Abilify before have diabetes or high blood sugar or a family history of diabetes or high blood sugar.
Your healthcare provider should check your blood sugar before you start receiving Abilify and during your treatment.
The median ingested aripiprazole dose was mg IQR: mg in the single-drug exposure group and mg IQR: mg in the mixed-drug exposure group. There were no malignant arrhythmias or ECG abnormalities after single-drug exposures. No deaths were recorded in relation to the intake.
In conclusion, we found that aripiprazole overdoses had few and mild symptoms predominantly related to the sedative properties. Some examples of mood stabilizers that may be taken with Abilify include:.
Your doctor may prescribe Abilify along with stimulants to treat your condition. Some examples of stimulants that may be taken with Abilify include:. Your doctor may prescribe Abilify along with other antipsychotic drugs to treat your condition. Some examples of other antipsychotics that may be taken with Abilify include:. Other drugs are available that can treat your condition. Some may be a better fit for you than others. They can tell you about other medications that may work well for you.
Note: Some of the drugs listed below are used off-label to treat these specific conditions. This means that Abilify is only used with other drugs for MDD.
Examples of other drugs that may be used to treat manic and mixed episodes related to bipolar I disorder include:. Examples of other drugs that may be used to treat schizophrenia include:.
You may wonder how Abilify compares with other medications that are prescribed for similar uses. Here we look at how Abilify and Abilify Maintena are alike and different. Both Abilify and Abilify Maintena contain the same active drug: aripiprazole. But even though these medications contain the same active drug, they act slightly differently inside your body. Abilify Maintena is approved to treat schizophrenia in adults. The typical dosage of this drug is mg given once each month.
Because Abilify and Abilify Maintena both contain the same active drug, their mild and serious side effects are the same. Also, because Abilify Maintena is an injectable medication, you may have pain at your injection site after receiving a dose of the drug. In some cases, you may actually start out by taking Abilify. Then if your condition responds well to the drug, you may start taking Abilify Maintena instead. One study looked at people who took Abilify and then transitioned to Abilify Maintena.
These people had more benefit in decreasing their schizophrenia symptoms when they switched to Abilify Maintena. But separate studies have found both Abilify and Abilify Maintena to be effective in treating schizophrenia.
According to estimates on GoodRx. The cost also depends on whether you receive doses of either drug from a pharmacy or a medical facility. Abilify and Abilify Maintena are both brand-name drugs. Brand-name medications usually cost more than generics cost. Like Abilify Maintena, discussed above, other medications are also prescribed for similar uses as Abilify is.
Here we look at how Abilify and Rexulti are alike and different. Abilify contains the active drug aripiprazole , while Rexulti contains the active drug brexpiprazole.
Both Abilify and Rexulti are approved to treat schizophrenia. For this use, Abilify can be prescribed for adults and children ages 13 years and older.
However, Rexulti is only approved for use in adults. Abilify and Rexulti are also both approved for use in adults as adjunct treatments for major depressive disorder MDD , which is also simply called depression.
Abilify and Rexulti both contain medications that treat schizophrenia and MDD. Therefore, these medications can cause very similar side effects, but some different ones as well.
Below are examples of these side effects. These lists contain up to 10 of the most common mild side effects that can occur with Abilify, with Rexulti, or with both drugs when taken individually. These lists contain examples of serious side effects that can occur with Abilify, with Rexulti, or with both drugs when taken individually.
And these medications can also each be used in combination with other drugs to treat MDD. The use of Abilify and Rexulti in treating schizophrenia has been directly compared in a clinical study. Abilify and Rexulti are both brand-name drugs. There is currently a generic form of Abilify, called aripiprazole. Brand-name medications usually cost more than generics. Like Rexulti, discussed above, other medications are prescribed for similar uses as Abilify is. Here we look at how Abilify and Latuda are alike and different.
Abilify contains the active drug aripiprazole , while Latuda contains the active drug lurasidone. Both Abilify and Latuda are approved to treat schizophrenia in adults and children ages 13 years and older. Abilify and Latuda both contain drugs to treat schizophrenia.
These lists contain up to 10 of the most common mild side effects that can occur with Abilify, with Latuda, or with both drugs when taken individually. These lists contain examples of serious side effects that can occur with Abilify, with Latuda, or with both drugs when taken individually. But separate studies have found both Abilify and Latuda to be effective in treating schizophrenia. Abilify and Latuda are both brand-name drugs. Controlled substances are more likely than other medications to cause dependence.
With dependence, your body needs the drug in order to feel normal. Abilify may cause dependence because it affects hormones inside your brain. And once your body adjusts to the changes caused by Abilify, you may become dependent on the drug.
However, keep in mind that dependence of Abilify has not been studied in humans. Because this medication may cause dependence and withdrawal symptoms, your doctor may recommend a different medication for you that has a lower risk of these complications. His symptoms included dizziness, nausea, anxiety, and muscle twitches. He also had insomnia trouble falling asleep or staying asleep.
But keep in mind that this case only involved one person. If you have questions about withdrawal symptoms from Abilify, talk with your doctor or pharmacist. With tapering, your doctor will slowly decrease your dose of the drug so that your body can adjust to the lower dose over time.
Tapering off of Abilify can help decrease your risk of withdrawal symptoms. Keep in mind that the lowest dose that Abilify tablets are made in is 2 mg. Abilify affects the levels of two brain chemicals called dopamine and serotonin.
Serotonin is important in controlling your mood and behavior. Dopamine is important in regulating how you think and feel. And Abilify is approved to treat each of these conditions. Abilify may work to treat certain mental health conditions by balancing dopamine and serotonin levels.
They can recommend whether you need medical attention. Yes, sometimes Abilify is used off-label to treat anxiety. And if you have questions about whether Abilify may be helpful in treating your anxiety, talk with your doctor.
Yes, Abilify may cause you to have dangerous impulses or urges. But all of these urges can be harmful, so you should tell your doctor, a family member, or a friend if you notice any impulses. In addition, your family and friends should also be keeping an eye out for any new impulses you may develop. This is important for them to do because you might not notice certain urges developing.
As soon as any urges or impulses are noticed, your doctor will likely decrease your dosage of Abilify. Or your doctor may have you stop taking the medication altogether. They can discuss with you the risks and benefits of treatment. These brain chemicals include dopamine and serotonin. And serotonin is important in controlling your mood and behavior.
Abilify may work by balancing your dopamine and serotonin levels. No, you should never take Abilify by snorting the drug. Abilify is meant to be taken by mouth. However, when you snort a drug through your nose, the drug goes directly into your bloodstream. In addition, snorting drugs can cause problems inside your nose, such as swelling or infections.
And in some cases , snorting drugs can even cause a hole to form between your nostrils. If you have questions about the best way to take your doses of Abilify, talk with your doctor or pharmacist. Yes, sometimes Abilify is used off-label to treat bipolar II disorder. On the other hand, Abilify is approved to treat manic or mixed episodes related to bipolar I disorder.
During these episodes, you can feel very energetic or extremely irritable. With mixed episodes, you have both manic symptoms and depression symptoms at the same time. This causes large changes in your mood. However, with bipolar II disorder, your most common symptom is major depression. Because people with bipolar II disorder mostly have depressive symptoms, Abilify may not work as well for them. If you have questions about using Abilify to treat bipolar II disorder, talk with your doctor.
They can recommend whether Abilify may be an option to treat your condition. In fact, for some people, Abilify may actually make them feel more sleepy than usual. Some drugs called stimulants may make you feel more energetic than usual.
Abilify belongs to a class of drugs called antipsychotics. A drug class describes a group of medications that work in the same way. Specifically, Abilify is a second-generation antipsychotic. Second-generation antipsychotics are a newer class of antipsychotic drugs. They cause fewer side effects than the first-generation antipsychotics do. Because there are many different mood disorders, there are also many different drug classes used to treat them.
For example, mood stabilizers, such as lithium , are drugs that help make your mood more consistent. In addition, Abilify is also not an antidepressant medication. Examples of antidepressants that are used with Abilify include:. Controlled substances are more likely than other drugs to cause dependence and withdrawal. So you may have some symptom relief in the first day or so after your first dose of Abilify.
Alcohol may cause dizziness, sleepiness, or trouble focusing. It may also decrease your blood pressure. Abilify can also cause these same side effects. Drinking alcohol and taking Abilify may increase your risk of these side effects. Using more than the recommended dosage of Abilify can lead to serious side effects. Do not use more Abilify than your doctor recommends.
In clinical trials , both intentional and accidental overdoses of Abilify in children and adults did occur. You can also call the American Association of Poison Control Centers at or use their online tool. But if your symptoms are severe, call or go to the nearest emergency room right away. Abilify can interact with several other medications. It can also interact with certain foods. Different interactions can cause different effects. For instance, some interactions can interfere with how well a drug works.
Other interactions can increase side effects or make them more severe. Below are lists of medications that can interact with Abilify. Before taking Abilify, talk with your doctor and pharmacist. Tell them about all prescription, over-the-counter, and other drugs you take. Also tell them about any vitamins, herbs, and supplements you use. Sharing this information can help you avoid potential interactions. If you have questions about drug interactions that may affect you, ask your doctor or pharmacist.
Abilify may interact with drugs that belong to a class of medications called benzodiazepines. A class of drugs describes a group of medications that work in the same way. Both Abilify and benzodiazepines can cause tiredness.
Taking Abilify with a benzodiazepine may worsen these effects. In some cases, your doctor may recommend that you take Abilify along with a benzodiazepine. However, because of the increased risk of side effects when doing this, your doctor will monitor your blood pressure.
If needed, your doctor may adjust your dosage of either Abilify or the benzodiazepine drug. Doing this can help to lower your risk of side effects. If you have any questions about the interactions between Abilify and benzodiazepines, talk with your doctor or pharmacist. Abilify may interact with certain antidepressant drugs. And Abilify may sometimes be used in combination with an antidepressant for other conditions as well.
This way, your doctor can determine if there are any drug interactions that may affect you. Specifically, Abilify may interact with certain antidepressants that belong to a class of drugs called selective serotonin reuptake inhibitors SSRIs. Taking either of these drugs with Abilify may increase the level of Abilify in your body.
And this could increase your risk of side effects from Abilify. If you have questions about interactions between Abilify and certain antidepressants, talk with your doctor or pharmacist.
Abilify is broken down in your liver by enzymes certain proteins. Taking Abilify with any drugs that affect these enzymes can alter the level of Abilify in your body. In some cases, the level will be increased, but in other cases, it will be decreased.
Below, we describe these possible interactions with Abilify. If you have any questions about which drugs may interact with Abilify, talk to your doctor or pharmacist. When this occurs, the level of Abilify in your body will be increased. And you may have an increased risk of side effects from Abilify.
Some medications induce prompt CYP3A4 to work faster than usual. When this occurs, the level of Abilify in your body will be decreased. And in this case, Abilify may not work as well to treat your condition. Abilify may interact with certain blood pressure medications , causing your blood pressure to become too low.
This effect happens because Abilify can also decrease your blood pressure. The combination of Abilify with a blood pressure medication can even cause very low blood pressure that may become dangerous. Abilify can interact with some recreational drugs, which may increase your risk of side effects from Abilify.
In addition, pain medications may also interact with Abilify. In these cases, the pain medications would be considered recreational.
Examples of pain medications that are sometimes used recreationally include:. All of the recreational drugs listed above may cause your heart rate to be slower than usual.
These drugs may also cause decreased blood pressure , sleepiness, and slowed breathing. Abilify can also decrease your blood pressure and cause sleepiness. So taking recreational drugs with Abilify may increase your risk of these side effects.
However, you should still check with your doctor or pharmacist before using any of these products while taking Abilify. Abilify is known to interact with grapefruit, which is described below. If you have any questions about consuming grapefruit or any other foods with Abilify, talk with your doctor. Anything that affects these enzymes can alter the level of Abilify in your body. When this occurs, the level of Abilify in your body is increased.
Animal studies have shown that, if used during pregnancy, Abilify may cause:. However, in these studies, animals were given much higher doses of Abilify than humans are given. They can discuss with you the risks and benefits of using this drug during pregnancy.
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