Your doctor will determine the best dosage to fit your needs. The recommended starting dosage of glipizide oral tablet for most adults with type 2 diabetes is 5 mg per day.
However, your doctor may recommend starting you with 2. You and your doctor will closely monitor your blood sugar levels after you start glipizide. If your blood sugar is still too high after a few days or weeks, your doctor will likely increase your dose. You may take glipizide IR tablets more than once per day.
For example, you may take one 5 mg tablet three times per day. The maximum dose of glipizide IR tablets is 40 mg total per day. You take glipizide ER tablets once per day with breakfast or your first meal of the day. The maximum dosage for glipizide ER tablets is 20 mg per day. If you miss your dose of glipizide, you should take it as soon as possible, but only if you plan to eat a meal, as follows:.
Regardless of which type of glipizide oral tablet you take IR or ER , you should not take two doses at the same time. Taking more than one dose can increase your risk of side effects such as hypoglycemia low blood sugar. To help make sure that you do not miss a dose, try using a medication reminder. This can include setting an alarm or downloading a reminder app on your phone.
A kitchen timer can work, too. Glipizide is meant to be used as a long-term treatment. Other drugs are available that can treat type 2 diabetes. Some may be a better fit for you than others. They can tell you about other medications that may work well for you. Note: Some of the drugs listed here are used off-label to treat these specific conditions.
However, weight gain has been commonly reported by people taking glipizide after glipizide IR tablets became available on the market. To help prevent or minimize weight gain, you should take glipizide alongside diet and exercise. Glipizide may cause more weight gain than other diabetes medications, such as metformin and sitagliptin.
If you have questions about weight changes with glipizide, talk with your doctor. They can talk with you about healthy ways to manage your weight. If you do not eat within 30 minutes of taking glipizide IR tablets or do not eat a meal with glipizide ER tablets, your blood sugar may drop too low.
This increases your risk of hypoglycemia low blood sugar. In some cases, hypoglycemia can become serious and may require urgent treatment. You should only take your dose of glipizide oral tablet if you plan to eat a meal. If your blood sugar reading is low 70 milligrams per deciliter or less , you should follow your hypoglycemia action plan as instructed by your doctor.
If you accidentally take glipizide but forget to eat, you should check your blood sugar. After about 3 months of glipizide treatment, your doctor will check your A1C. If glipizide is working the way it should, you may notice that your blood sugar readings are within or close to your goal range. If you have questions about what to expect from your glipizide treatment, talk with your doctor.
They can also give you more information about your A1C and blood sugar goal ranges. However, glipizide may not be safe for some people who already have kidney problems, such as kidney disease. People with kidney problems have a higher risk of developing hypoglycemia low blood sugar.
Before starting glipizide, tell your doctor if you have a history of kidney problems. They may start you on a low dosage of the drug or suggest a different medication. For more information on possible side effects, see the prescribing information for glipizide IR oral tablets and glipizide ER oral tablets.
Taking your diabetes medications correctly and following a balanced diet and lifestyle may help manage your blood sugar. This may help prevent or reduce hair loss. If you have questions about hair loss, talk with your doctor.
They may want to do a check-up or use blood tests to look for other possible causes. Drinking alcohol may increase your risk of hypoglycemia low blood sugar with glipizide. It may also increase the frequency or severity of certain side effects, such as nausea and dizziness. There have also been rare reports of severe reactions when glipizide IR tablets were taken with alcohol.
These reactions occurred after glipizide IR tablets became available on the market. These severe reactions are called disulfiram-like reactions. Symptoms of disulfiram-like reactions may include severe nausea and vomiting , flushing , and heart rate and blood pressure changes.
For more information on these reactions, see prescribing information on glipizide IR oral tablets and glipizide ER oral tablets. Alcohol consumption may also make it harder for you to manage your blood sugar. For more information about drinking alcohol with diabetes, talk with your doctor. You can ask them how much alcohol if any is safe for you to drink while taking glipizide.
Glipizide oral tablets can interact with several other medications. Different interactions can lead to different effects. For instance, some interactions can interfere with how well a drug works. Other interactions can increase side effects or make them more severe.
Before taking glipizide oral tablets, talk with your doctor and pharmacist. Tell them about all prescription, over-the-counter, and other drugs you take. Also, tell them about any vitamins, herbs, and supplements you take. Sharing this information can help you avoid potential interactions. Below is a list of medications that can interact with glipizide oral tablets.
This list does not contain all drugs that may interact with glipizide. Certain types of drugs can increase the risk of hypoglycemia low blood sugar or worsen hypoglycemia when taken with glipizide. Careful monitoring of blood sugar levels is needed if you take these drugs with glipizide. Examples of these drugs include:. Certain drugs can affect how well glipizide manages your blood sugar. This is because they can cause hyperglycemia high blood sugar.
Colesevelam WelChol can also cause glipizide ER tablets to be less effective. Because of this risk, you should take glipizide ER tablets at least 4 hours before taking colesevelam.
Other drugs may interact with glipizide oral tablets. If you have questions about drug interactions that may affect you, ask your doctor or pharmacist. However, some herbs and supplements can possibly lower your blood sugar. This may increase your risk of hypoglycemia low blood sugar with glipizide. If you have any questions about eating certain foods with Glipizide oral tablets, talk with your doctor. Glipizide oral tablets are prescription generic drugs that you take along with diet and exercise to manage blood sugar in adults with type 2 diabetes.
Usually, when you eat a meal, the carbohydrates sugar from your food gets absorbed into your bloodstream. Your pancreas then releases insulin. Insulin is a hormone that signals your body to move sugar out of your bloodstream and into your cells. This causes your blood sugar to stay high. Glipizide IR tablets begin to lower your blood sugar 30 minutes after you take a dose. The drug reaches its full effects 1 to 3 hours after each dose. You may not notice glipizide oral tablets working in your body.
In most cases, the only way to determine if the drug is working is to check your blood sugar level. Talk with your doctor about how often you should check your blood sugar. They can tell you what your goal range should be. The effects of glipizide IR tablets begin to wear off about 3 hours after you take your dose. But the drug may continue to help manage your blood sugar for up to 24 hours after each dose.
Glipizide ER tablets slowly release the active drug into your body. The drug reaches its full effects 6 to 12 hours after each dose. After taking glipizide ER tablets once daily for 5 days in a row, the medication reaches a steady level in your system. Glipizide pronounced as glip' i zide.
Why is this medication prescribed? How should this medicine be used? Other uses for this medicine What special precautions should I follow? What special dietary instructions should I follow?
What should I do if I forget a dose? What side effects can this medication cause? What should I know about storage and disposal of this medication? Brand names Brand names of combination products.
Swallow the extended-release tablets whole. Do not chew, divide, or crush the tablets. Ask your pharmacist or doctor for a copy of the manufacturer's information for the patient. Other uses for this medicine. What special precautions should I follow? Before taking glipizide, tell your doctor and pharmacist if you are allergic to glipizide, any other medications, or any of the ingredients in glipizide.
Ask your pharmacist for a list of the ingredients. Also be sure to tell your doctor or pharmacist if you stop taking any medications while taking glipizide. Your doctor may need to change the doses of your medications or monitor you carefully for side effects. If you are taking the extended-release tablet, tell your doctor if you have short bowel syndrome a condition where part of the intestine has been removed by surgery, damaged by disease, or you were born without part of your intestines ; you have narrowing or a blockage of the intestines; or if you have ongoing diarrhea.
If you become pregnant while taking glipizide, call your doctor. Alcohol may make the side effects of glipizide worse. Consuming alcohol while taking glipizide also rarely may cause symptoms such as flushing reddening of the face , headache, nausea, vomiting, chest pain, weakness, blurred vision, mental confusion, sweating, choking, breathing difficulty, and anxiety.
Glipizide may make your skin sensitive to sunlight. These conditions can affect your blood sugar and the amount of glipizide you may need. This medication may cause changes in your blood sugar. You should know the symptoms of low and high blood sugar and what to do if you have these symptoms.
Glipizide may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away: diarrhea gas feeling jittery dizziness uncontrollable shaking of a part of the body red or itchy skin rash hives blisters Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately: yellowing of the skin or eyes light-colored stools dark urine pain in the upper right part of the stomach unusual bruising or bleeding fever sore throat Glipizide may cause other side effects.
Symptoms of overdose may include hypoglycemia symptoms as well as the following: seizures loss of consciousness. If you pass out because of a low sugar reaction or cannot swallow, someone will have to give an injection of glucagon to treat the low sugar reaction. You may need to go to the emergency room. If you have an allergic reaction, call your doctor or local poison control center right away.
If your symptoms are severe, call or go to the nearest emergency room. Taking it again could be fatal. When taken with alcohol, this drug can cause an unpleasant sensation called disulfiram reaction. Symptoms of this reaction can include:. For people with liver problems: If you have liver problems, you may not be able to clear this drug from your body as well as you should. Glipizide may build up in your body, which can cause lower blood sugar levels.
For people with kidney problems: If you have kidney problems, you may not be able to clear this drug from your body as well as you should. For people who are sick, injured, or plan to have surgery: If you have a fever, trauma, infection, or surgery, you may not be able to control your blood sugar levels with this drug.
Your doctor may give you insulin temporarily instead. You could get anemia. Use insulin to treat this condition instead. For pregnant women: Research in animals has shown negative effects to the fetus when the mother takes this drug. Small studies in pregnant women have not shown significant effects to the fetus when the mother takes the drug. However, they have shown some low blood sugar effects in newborns. For this reason, the extended-release form of glipizide should be stopped at least two weeks before delivery.
The immediate-release form should be stopped at least one month before delivery. If it does, it may cause serious effects in a breastfeeding child. For seniors: Your body may process this drug more slowly. Your doctor may start you on a lowered dose to stop too much of the drug from building up in your body. Too much of the drug in your body can be toxic. Glipizide is used for long-term treatment. Symptoms can include:. If you take too much: If you take too much glipizide, your low blood sugar levels may get very low.
But if your symptoms are severe, call or go to the nearest emergency room right away. What to do if you miss a dose: If you forget to take your dose, take it as soon as you remember. Never try to catch up by taking two doses at once.
This could result in toxic side effects. How to tell if the drug is working: You may be able to tell if this drug is working if you have a decrease in your blood sugar levels and your symptoms of diabetes get better. For instance, you may not be as thirsty or hungry, and you may not urinate as often. A prescription for this medication is refillable. You should not need a new prescription for this medication to be refilled. Your doctor will write the number of refills authorized on your prescription.
Your doctor or pharmacist will show you how to test your blood sugar at home using a blood glucose monitor. These may include:. During your treatment with glipizide, follow the nutrition plan that your doctor, registered dietitian, or diabetes educator has recommended.
There are other drugs available to treat your condition. Some may be more suitable for you than others. Talk to your doctor about possible alternatives. Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up-to-date.
However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional.
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